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Zinc finger protein 627 (ZNF627)
- Target
- ZNF627
- Molecular classification
- Transcription factor (specifically, a DNA-binding transcription factor with C2H2-type zinc fingers and a Kruppel-associated box (KRAB) domain), Other: Protein coding gene
01
Overview
Zinc finger protein 627 (ZNF627) is a human protein-coding gene located on chromosome 19. It is predicted to function as a DNA-binding transcription factor, specifically regulating transcription mediated by RNA polymerase II. The protein contains 11 C2H2-type zinc fingers and a Kruppel-associated box (KRAB) domain, characteristic of a large family of transcriptional regulators involved in gene expression modulation. ZNF627 primarily localizes in the nucleus, consistent with its predicted role as a transcriptional regulator. There are currently no well-established biological functions beyond transcriptional regulation, and no recognized disease associations, interacting drugs, or clinical biomarker applications for this protein. The gene is expressed across various human tissues, but its specific physiological roles remain incompletely characterized.
- Other names
- ZNF627FLJ90365Zinc finger protein 627
02
Mechanism of action
Not applicable. No drugs currently target this protein, and no mechanisms of action have been described or proposed.
03
Biological functions
Regulation of transcription by RNA polymerase IIRNA polymerase II regulatory region sequence-specific DNA bindingNucleic acid binding (predicted)
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