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Target intelligence / Profile preview
Zinc finger protein 652 (ZNF652)
- Target
- ZNF652
- Molecular classification
- Transcription factor, Zinc finger protein
01
Overview
Zinc finger protein 652 is a transcription factor that acts as a DNA-binding transcriptional repressor, predicted to regulate transcription by RNA polymerase II and to be localized in the nucleus. It has been associated with diseases including prostate cancer, and studies suggest roles in the regulation of cell proliferation and migration in cancer contexts. There is no evidence that ZNF652 is currently a direct therapeutic target, nor are specific drugs or clinical biomarkers known to interact with or utilize ZNF652 for patient selection or efficacy monitoring.
- Other names
- KIAA0924GC17M044728GC17M047366GC17M042731GC17M049289GC17M049395GC17M052168GC17M054655GC17M057560GC17M061295GC17M064659GC17M068576GC17M072152GC17M078179GC17M085580GC17M089723GC17M093772
02
Biological functions
Regulation of transcription by RNA polymerase IITranscriptional repressionDNA binding
03
Disease associations
Cancer (notably prostate cancer)Other (based on reported associations with proliferation, migration, and invasion in osteosarcoma models)
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