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Zinc finger protein 664 (ZNF664)
- Target
- ZNF664
- Molecular classification
- Transcription factor, DNA-binding protein, Zinc finger protein
01
Overview
Zinc finger protein 664 (ZNF664) is a DNA-binding transcription factor predicted to play a role in the regulation of gene expression via RNA polymerase II-dependent transcription. It contains zinc finger motifs, which are common structural domains that facilitate sequence-specific DNA binding in the nucleus. ZNF664 is associated with some congenital diseases, such as autosomal dominant deafness and clubfoot, but its detailed mechanistic involvement in pathophysiology is not well characterized[3][5][8]. No known drugs currently target ZNF664, and it is not established as a therapeutic target.
- Other names
- ZNF664ZFOC1ZNF176Zinc finger protein 176Zinc finger protein from organ of CortiZinc finger, organ of Corti 1DKFZp761B128
02
Biological functions
Transcriptional regulationDNA bindingGene expression
03
Disease associations
Deafness (Autosomal dominant 41)Clubfoot
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