Zinc finger protein 708 (ZNF708)

Zinc finger protein 708 (ZNF708) is a member of the zinc finger family of transcription factors. It contains classical C2H2-type zinc finger domains that enable it to bind DNA and regulate transcription, probably through interaction with RNA polymerase II-specific cis-regulatory regions[2][4]. The zinc finger protein family is the most abundant transcription factor class in eukaryotes, playing roles in genome stability, DNA damage repair, and cell proliferation[1]. ZNF708 is predicted to act in the regulation of DNA-templated transcription and is expressed in many tissues[2][3]. While some zinc finger proteins are established as therapeutic targets due to their roles in disease, ZNF708 itself is not yet a characterized target for drug development, nor are there established drugs or mechanisms of action involving this protein[2][4]. Diseases associated with ZNF708 include certain ovarian and testicular cancers, but its direct role in these diseases remains unclear[2].

Other names

ZNF708Zinc finger protein 708KOX8ZNF15ZNF15L1Zinc finger protein 15Zinc finger protein 15-like 1Zinc finger protein KOX8