Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Zinc finger protein 717 (ZNF717)
- Target
- ZNF717
- Molecular classification
- Transcription factor, Zinc finger protein, Kruppel-associated box (KRAB) domain protein
01
Overview
Zinc finger protein 717 is a member of the Kruppel-associated box (KRAB) zinc-finger family of transcriptional regulators in mammals[1][2][3][9]. It binds nucleic acids and plays roles in regulating gene expression, cell proliferation, differentiation, apoptosis, and viral replication and transcription[1][2][3][9][10]. It may act as a tumor suppressor by regulating the IL-6/STAT3 signaling pathway in hepatocellular carcinoma and is associated with mutation in several cancers[3][11]. There is currently no direct evidence that ZNF717 is a primary therapeutic target, nor are there known drugs that selectively interact with it.
- Other names
- ZNF717X17Krueppel-like factor X17OB1ZNF838zinc finger protein 838kruppel-like zinc finger factor X17
02
Biological functions
Transcription regulationCell proliferationCell differentiationApoptosisRegulation of viral replication
03
Disease associations
Cancer (notably hepatocellular carcinoma, prostate cancer)
Beyond the preview
Go deeper on Zinc finger protein 717 (ZNF717).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Zinc finger protein 717 (ZNF717).