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Zinc finger protein 747 (ZNF747)
- Target
- ZNF747
- Molecular classification
- Transcription factor, Zinc finger protein (C2H2-type), KRAB domain-containing protein
01
Overview
Zinc finger protein 747 is a member of the large C2H2-type zinc finger protein family, designated by the human gene symbol ZNF747. It contains a KRAB (Krüppel-associated box) domain, which typically mediates transcriptional repression. ZNF747 is predicted to function primarily as a DNA-binding transcriptional regulator, influencing gene expression through zinc ion-dependent interactions with nucleic acids. The protein is expressed in various human tissues, but specific biological roles, disease associations, or clinical relevance remain largely uncharacterized, and it is not listed among recognized therapeutic targets in current databases[1][3][5][7][8].
- Other names
- ZNF747KRAB domain-containing protein ZNF747MGC2474
02
Biological functions
Regulation of DNA-templated transcriptionZinc ion bindingNucleic acid binding
03
Disease associations
Other (limited disease association; Coumarin resistance is reported, but no major disease role established)
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