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Zinc finger protein 763 (ZNF763)
- Target
- ZNF763
- Molecular classification
- Transcription factor, Zinc finger protein
01
Overview
Zinc finger protein 763 is a human protein encoded by the ZNF763 gene and is predicted to function as a transcription factor by binding DNA in a sequence-specific manner via RNA polymerase II regulatory regions. It is part of the C2H2-type zinc finger family, which is the largest group of zinc finger proteins, typically acting as transcriptional regulators. ZNF763 is localized to the nucleus and may be involved in regulating gene expression, but its precise biological function and clinical relevance as a drug target remain to be established. Diseases associated with ZNF763 include some neurodevelopmental and neurodegenerative conditions, but there are no known drugs directly targeting this protein[2][6][7][3].
- Other names
- Zinc finger protein 763ZNF763ZNF440Lzinc finger protein 440 likeDNA-binding protein
02
Biological functions
Regulation of transcriptionDNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA binding
03
Disease associations
Autosomal dominant intellectual developmental disorder 40Frontotemporal dementia and/or amyotrophic lateral sclerosis 7
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