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Target intelligence / Profile preview
Zinc finger protein 771 (ZNF771)
- Target
- ZNF771
- Molecular classification
- Transcription factor, Zinc finger protein (C2H2-type)
01
Overview
Zinc finger protein 771 (ZNF771) is a member of the zinc finger protein family, specifically of the C2H2-type, and functions as a sequence-specific double-stranded DNA binding transcription factor. It is thought to play key roles in the regulation of gene expression by RNA polymerase II, impacting processes such as cell growth, differentiation, and development. ZNF771 is primarily localized in the nucleolus and nucleoplasm and is predicted to modulate transcriptional programs essential for normal cellular function. Dysregulation of ZNF771 has been linked to several diseases, including cancer, cardiovascular disorders, neurological conditions, and has been associated with Wolf-Hirschhorn syndrome. Currently, ZNF771 is not classified as a direct therapeutic target and no drugs are reported to act specifically on this protein. However, its status as a transcriptional regulator and biomarker in cancer and other diseases makes it a molecule of interest for further research and potential future therapeutic targeting.
- Other names
- Zinc finger protein 771ZNF771DSC43Mesenchymal stem cell protein DSC43
02
Biological functions
Transcriptional regulationSequence-specific DNA bindingCell growthCell differentiationDevelopment
03
Disease associations
CancerCardiovascular diseaseNeurological conditionsWolf-Hirschhorn syndrome
04
Biomarkers
CancerCardiovascular disordersNeurological conditions
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