Target intelligence / Profile preview

Zinc finger protein 772 (ZNF772)

Target
ZNF772
Molecular classification
Transcription factor, DNA-binding protein, C2H2-type zinc finger protein
01

Overview

Zinc finger protein 772 is a member of the C2H2-type zinc finger transcription factor family, which is among the most abundant DNA-binding proteins in eukaryotes[1][3][5]. ZNF772 functions in the nucleus and is thought to regulate gene expression by binding to specific DNA sequences, modulating transcription via RNA polymerase II[3][5][9][11]. It is not generally targeted by drugs and has no established role as a therapeutic target. Disease association data suggest links to certain cancers (notably prostate cancer), but mechanistic or clinical significance remains limited or unclear[5][9][11]. The protein belongs to a structurally diverse group whose roles, although primarily related to gene regulation, may extend to other processes including apoptosis, though specific functional data for ZNF772 remain sparse[1].

Other names
ZNF772DKFZp686I1569zinc finger protein 772
02

Biological functions

Regulation of transcriptionDNA bindingRNA polymerase II cis-regulatory region binding
03

Disease associations

Cancer (associated with prostate cancer)

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