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Zinc finger protein 789 (ZNF789)
- Target
- ZNF789
- Molecular classification
- Transcription factor, Zinc finger protein, C2H2-type zinc finger family
01
Overview
Zinc finger protein 789 (ZNF789) is a predicted DNA-binding transcription factor in humans, associated with the C2H2-type zinc finger protein family. Like other zinc finger proteins, ZNF789 is thought to bind specific DNA sequences via its zinc-coordinated finger motifs, thereby regulating gene expression typically by RNA polymerase II. ZNF789 localizes to the nucleoplasm and is predicted to function as a sequence-specific transcriptional regulator. The zinc finger family more broadly is known for regulating diverse cellular processes including transcription, cell cycle control, and DNA repair. While ZNF789 has functional associations with various genes and is linked to certain tumors, its precise biological roles and potential as a therapeutic target remain uncharacterized in the literature.
- Other names
- ZNF789Zinc finger protein 789
02
Biological functions
Regulation of transcription by RNA polymerase IISequence-specific DNA binding
03
Disease associations
Cancer (Noted association: Adult pineoblastoma and adult pineal parenchymal tumor, but mechanism not elucidated)
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