Target intelligence / Profile preview

Zinc finger protein 804B (ZNF804B)

Target
ZNF804B
Molecular classification
Transcription factor, Zinc finger protein, C2H2-type zinc finger superfamily
01

Overview

Zinc finger protein 804B (ZNF804B) is a protein predicted to function as a transcription factor based on its zinc finger domains, specifically the C2H2-type, which are common DNA-binding motifs. The protein is primarily predicted to reside in the nucleus and enable metal ion (zinc) binding[2][3][5][11]. Its gene encodes a large protein believed to play a role in transcription regulation—a general function of the zinc finger protein family[4][1][7][9]. There is some evidence linking ZNF804B to neuropsychiatric conditions, such as autism spectrum disorder[11], but its specific biological roles and molecular mechanisms are not well-characterized. No drugs or clinical interventions currently target ZNF804B, and it is absent from most lists of established therapeutic targets or clinical biomarkers. In summary, ZNF804B is a zinc finger transcription factor with putative DNA-binding capability, very limited disease association, and no current indication as a direct therapeutic target.

Other names
ZNF804BFLJ32110zinc finger 804BZinc finger protein 804B
02

Biological functions

Predicted transcription regulationMetal ion binding (specifically zinc)Possible involvement in metabolic processes, homeostasis, and regulation of molecular function
03

Disease associations

Associated with Autism Spectrum Disorder (limited evidence)Other: There is currently no strong disease association; roles in cancer or other major diseases have not been described for ZNF804B specifically.

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