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Zinc finger protein 804B (ZNF804B) is a protein predicted to function as a transcription factor based on its zinc finger domains, specifically the C2H2-type, which are common DNA-binding motifs. The protein is primarily predicted to reside in the nucleus and enable metal ion (zinc) binding[2][3][5][11]. Its gene encodes a large protein believed to play a role in transcription regulation—a general function of the zinc finger protein family[4][1][7][9]. There is some evidence linking ZNF804B to neuropsychiatric conditions, such as autism spectrum disorder[11], but its specific biological roles and molecular mechanisms are not well-characterized. No drugs or clinical interventions currently target ZNF804B, and it is absent from most lists of established therapeutic targets or clinical biomarkers. In summary, ZNF804B is a zinc finger transcription factor with putative DNA-binding capability, very limited disease association, and no current indication as a direct therapeutic target.
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