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Zinc finger protein 846 (ZNF846)
- Target
- ZNF846
- Molecular classification
- Transcription factor, Protein coding gene
01
Overview
Zinc finger protein 846 (ZNF846) is a human protein encoded by the ZNF846 gene on chromosome 19 that is predicted to act as a sequence-specific DNA-binding transcription factor, particularly involved in transcriptional regulation mediated by RNA polymerase II[1][3][4][6][7][8]. It contains zinc finger domains characteristic of this protein family and is predicted to be active in the cell nucleus. There is limited direct evidence describing its precise physiological or pathological role, but an association has been noted with microcephalic osteodysplastic primordial dwarfism, type II[1]. No data were found indicating its use as a therapeutic target, drug interactions, or utility as a biomarker.
- Other names
- ZNF846Zinc finger protein 846LOC100505555Zinc finger protein 420 pseudogene
02
Biological functions
Regulation of transcription by RNA polymerase IISequence-specific DNA bindingNucleic acid binding
03
Disease associations
Possible association with microcephalic osteodysplastic primordial dwarfism, type II
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