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Zinc finger protein 85 (ZNF85)
- Target
- ZNF85
- Molecular classification
- Transcription factor
01
Overview
Zinc finger protein 85 (ZNF85) is a member of the zinc finger protein family, characterized by tandem C2H2-type zinc finger domains that enable sequence-specific DNA binding. ZNF85 is primarily thought to act as a transcriptional repressor, possibly modulating gene expression by binding to specific cis-regulatory regions recognized by RNA polymerase II. The ZNF85 gene is expressed in various tissues, notably with high expression in normal adult testes and certain testicular tumors, and is located on chromosome 19. Like other zinc finger proteins, it may participate in controlling diverse biological processes, but there are currently no known drugs or therapeutic indications directly targeting ZNF85[2][3][4][5][8][10].
- Other names
- Zinc finger protein HPF4Zinc finger protein HTF1HPF4HTF1
02
Biological functions
Transcriptional repressionRegulation of DNA-templated transcriptionSequence-specific DNA binding
03
Disease associations
Other (reported associations with testis pathology and thrombocytopenia, but no established direct disease role as a target)
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