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Target intelligence / Profile preview
Zinc finger protein 883 (ZNF883)
- Target
- ZNF883
- Molecular classification
- Transcription factor, Zinc finger protein, C2H2-type zinc finger protein
01
Overview
Zinc finger protein 883 (ZNF883) is a protein-coding gene predicted to function as a transcription factor, specifically enabling sequence-specific DNA binding and regulation of transcription by RNA polymerase II[1][2][10][12]. It belongs to the C2H2-type zinc finger family and is predicted to be located in the nucleus, where it may participate in transcriptional regulation[2][4][6][12]. While the specific biological or pathological roles of ZNF883 in human disease are not well characterized, it shares structural features with other zinc finger transcription factors that generally play roles in modulating gene expression. No known drugs, drug mechanisms, biomarkers, or significant safety concerns have been attributed to this gene to date[11][12].
- Other names
- ZNF883Zinc finger protein 883ZN883_HUMANHGNC:27271NCBI Gene: 169834Ensembl: ENSG00000228623UniProt: P0CG24
02
Biological functions
Regulation of transcription by RNA polymerase IISequence-specific DNA-bindingPossible involvement in RNA polymerase II cis-regulatory region binding
03
Disease associations
Other (no specific disease roles identified)
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