Target intelligence / Profile preview

Zinc finger protein 92 (ZNF92)

Target
ZNF92
Molecular classification
Transcription factor, C2H2-type zinc finger protein, DNA-binding protein
01

Overview

Zinc finger protein 92 (ZNF92) is a member of the C2H2-type zinc finger protein family, which is characterized by the presence of one or more zinc finger domains that coordinate zinc ions to stabilize their fold and facilitate DNA binding[1][4][5]. ZNF92 is predicted to act as a sequence-specific transcription factor, binding DNA at RNA polymerase II cis-regulatory regions and regulating transcription of target genes[1]. Like other zinc finger proteins, ZNF92 is believed to reside in the nucleus and may be involved in diverse cellular processes related to gene expression and transcriptional regulation[1][4]. However, ZNF92 itself is not prominently featured as a therapeutic target, nor is it directly linked to prominent human diseases in current literature[1][3]. **Key context:** - ZNF92 is catalogued as a protein-coding gene with nucleic acid-binding and DNA-binding transcription factor activity per gene ontology annotations[1]. - It is part of the large and diverse family of zinc finger proteins, the majority of which function as transcriptional regulators throughout eukaryotic genomes[4][5]. - Unlike enzyme, receptor, or transporter targets, ZNF92 is classified specifically as a transcription factor and is therefore not typically considered a classic druggable target.

Other names
ZNF92ZNF92_HUMANQ03936
02

Biological functions

Regulation of gene expressionDNA-bindingTranscriptional regulationRNA polymerase II cis-regulatory element binding
03

Disease associations

Other (no direct association with major diseases reported; zinc finger proteins are frequently implicated in diverse pathologies but ZNF92 itself has no strongly documented links to specific conditions)

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