ZKSCAN8 pseudogene 1 (ZKSCAN8P1)

ZKSCAN8 pseudogene 1 (ZKSCAN8P1) is a non-coding genomic locus classified as a pseudogene of the zinc finger with KRAB and SCAN domains protein family. Pseudogenes are typically non-functional DNA sequences resembling protein-coding genes but lack protein-coding capability, and therefore do not have known biological functions or clinical roles. ZKSCAN8P1 shares sequence similarity to ZKSCAN8 (Zinc finger with KRAB and SCAN domains 8), which is a transcription factor potentially involved in transcriptional regulation, but ZKSCAN8P1 itself is not believed to produce a functional protein and is not implicated as a therapeutic target or biomarker. ZKSCAN8P1 is assigned pseudogene status and is not protein-coding. The canonical related protein, ZKSCAN8, is categorized among zinc finger transcription factors involved in gene expression regulation, but ZKSCAN8P1 does not share this function. Functional annotations (GeneCards, BioGPS) highlight metal ion binding activity only as a predicted capability based on sequence similarity, not actual function. No published data indicate a role in disease, drug interaction, or use as a biomarker. Thus, ZKSCAN8P1 is best classified as a non-coding pseudogene with no established functional or therapeutic relevance.

Other names

dJ265C24.4ZNF389PZNF389ZNF192P1zinc finger protein 389, pseudogenezinc finger protein 192 pseudogene 1