Target intelligence / Profile preview

ZNF32 antisense RNA 1 (ZNF32-AS1)

Target
ZNF32-AS1
Molecular classification
Long non-coding RNA (lncRNA), Antisense RNA, Other
01

Overview

ZNF32 antisense RNA 1 (ZNF32-AS1) is a long non-coding RNA (lncRNA) located on human chromosome 17, also known by aliases including ZNF32OS1 and bA402L1.8[1][2][4]. It does not code for a protein but is thought to play a regulatory role in cellular processes, particularly by modulating gene expression[1][3]. ZNF32-AS1 is classified as an antisense RNA because it is transcribed from the DNA strand opposite the protein-coding ZNF32 gene[1]. Emerging evidence indicates that dysregulation of ZNF32-AS1 occurs in various cancers, suggesting a possible role in tumorigenesis, though its precise biological functions and mechanisms remain unclear[1][2][3]. There are currently no known drugs, biomarker roles, or established safety concerns directly linked to ZNF32-AS1.

Other names
ZNF32OS1bA402L1.8ZNF32 antisense RNA 1 (non-protein coding)zinc finger protein 32 opposite strand 1
02

Biological functions

Regulation of gene expressionPotential involvement in tumorigenesisPossible regulatory role in chromatin structure and transcriptional activity
03

Disease associations

Cancer (dysregulated in various cancers, possible role in tumorigenesis)

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