ZNF350 antisense RNA 1 (ZNF350-AS1)

ZNF350 antisense RNA 1 (ZNF350-AS1) is a long non-coding RNA (lncRNA) gene located at chromosome 19q13.41 that does not encode a protein but instead regulates gene expression and chromatin state, often by acting as an antisense regulator for the nearby ZNF350 gene[1][4][5]. ZNF350-AS1 is reported under several aliases, notably HCCAT3, and has been implicated in the progression of multiple cancers, including hepatocellular carcinoma where its upregulation may facilitate tumor growth[3][4]. Its mechanisms include recruiting transcription factors, influencing enhancer activity, regulating alternative splicing, and potentially participating in RNA editing events[1][4]. While evidence suggests a role as a biomarker for some cancer types, there are currently no known drug interactions or targeted therapeutic agents, nor is it categorized as a therapeutic target such as a receptor or enzyme[2][3][4].

Other names

HCCAT3uc002pycCTC-429C10.4hepatocellular carcinoma associated transcript 3 (non-protein coding)