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Target intelligence / Profile preview
ZNF436 antisense RNA 1 (ZNF436-AS1)
- Target
- ZNF436-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Non-coding RNA, Other
01
Overview
ZNF436 antisense RNA 1 (ZNF436-AS1) is a long non-coding RNA gene located on chromosome 1 (specifically at 1p36.12) and designated by gene ID 148898[4][10]. It produces an RNA molecule that does not encode a protein but is believed to be involved in regulating gene expression, cell growth, and differentiation. ZNF436-AS1 interacts with protein-coding genes such as ZNF436 and may influence transcription factor activity. Dysregulation of ZNF436-AS1 expression has been observed in multiple cancer types and is implicated in cancer development and progression. Its biological and clinical significance are being actively investigated, with current evidence supporting a role in oncogenic and cellular processes but not as a direct therapeutic target[1][9][13].
- Other names
- ZNF436-AS1C1orf213FLJ90508ZNF436 antisense gene protein 1Putative uncharacterized protein ZNF436-AS1
02
Biological functions
Regulation of gene expressionCell proliferationCell differentiationApoptosisPossible regulation of transcription factor activity (interacts with ZNF436 protein)
03
Disease associations
CancerGlioma susceptibility
04
Biomarkers
Dysregulated expression in various cancers (potential biomarker role suggested but not regularly used clinically)
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