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Target intelligence / Profile preview
ZNF45 antisense RNA 1 (ZNF45-AS1)
- Target
- ZNF45-AS1
- Molecular classification
- Long non-coding RNA, Antisense RNA, Other
01
Overview
ZNF45 antisense RNA 1 (ZNF45-AS1) is a long non-coding RNA gene located on chromosome 19, transcribed in antisense orientation relative to the protein-coding ZNF45 locus. Like other antisense lncRNAs, ZNF45-AS1 is likely involved in regulating the expression of its sense gene counterpart (ZNF45) or neighboring genes through mechanisms such as transcriptional interference or modulation of RNA stability. As with other lncRNA antisense transcripts, its function may include guiding chromatin-modifying complexes, influencing chromatin structure, or participating in cis- or trans-regulatory networks. However, ZNF45-AS1 has no currently documented direct links to diseases or pharmacological interventions in public genetic or biomedical databases.
- Other names
- ZNF45-AS1ZNF45 antisense RNA 1
02
Mechanism of action
Not applicable; no current evidence of therapeutically targeting this lncRNA.
03
Biological functions
Regulation of gene expression (likely through antisense mechanisms involving interference with transcription or transcript stability)May modulate the expression of overlapping or neighboring genes, such as ZNF45
04
Disease associations
No direct disease associations described in curated sources as of the current data, but other antisense RNAs have recognized roles in cancer and gene regulation disordersNo specific disease roles for ZNF45-AS1 itself currently documented
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