ZNF680 pseudogene 1 (ZNF680P1)

**ZNF680 pseudogene 1** (ZNF680P1) is a **non-coding pseudogene** that has sequence similarity to the canonical Zinc finger protein 680 gene (ZNF680). Pseudogenes like ZNF680P1 are generally considered functionless remnants of evolution, usually lacking protein-coding capacity due to disabling mutations such as frameshifts or premature stop codons[5][8]. Some pseudogenes have been shown to give rise to regulatory non-coding RNAs with epigenetic or RNA interference activity, but this is gene-specific and has not been demonstrated for ZNF680P1[2][3][8]. There is no evidence that ZNF680P1 acts as a receptor, enzyme, transporter, or drug target. Furthermore, ZNF680P1 is not recognized as a biomarker, nor implicated in known disease processes. Its existence is mainly of interest in studies of gene evolution and the regulatory potential of non-coding genomic elements[2][3][5][8]. **Note:** There may be confusion because ZNF680 is an active protein-coding gene, and some information about zinc finger proteins and their disease associations concern ZNF680 or its family—not the pseudogene ZNF680P1 specifically[1][6]. Thus, ZNF680P1 is neither a canonical therapeutic target nor an established functional regulator.