Zona pellucida glycoprotein 3 pseudogene 1 (ZP3P1)

ZP3P1 is a pseudogene that closely resembles the functional gene ZP3, which encodes a key glycoprotein in the zona pellucida of the oocyte and serves as the sperm receptor necessary for fertilization[1]. However, ZP3P1 does not encode a functional protein and lacks biological, diagnostic, or therapeutic roles[5]. Its annotation as a pseudogene means it has sequences similar to ZP3 but has lost the capacity to be translated into a functional protein due to mutations or genomic rearrangements[5]. The functional receptor and key biological molecule relevant to fertilization is ZP3, not ZP3P1[1]. For structured data, ZP3P1 should not be considered a biological or therapeutic target.

Other names

ZP3P1zona pellucida glycoprotein 3 (sperm receptor) pseudogenezona pellucida sperm receptor pseudogene

None—no pharmacological mechanism, as no drugs target ZP3P1.