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Phase II dose-escalation study of Zevalin before BEAM and autologous stem cell transplantation in relapsed or refractory aggressive non-Hodgkin lymphoma

2004-003801-26Phase 2Completed

Sponsor
Institut für anwendungsorientierte Forschung und klinische Studien
Start
Nov 2004
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of ibritumomab tiuxetan in non-Hodgkin lymphoma (NHL) and aggressive lymphoma, sponsored by Institut für anwendungsorientierte Forschung und klinische Studien. Primary endpoints: Maximum usable dose of yttrium-90 Zevalin before BEAM and autologous stem cell transplantation and Frequency of grade III and IV pulmonary toxicity. Started Nov 2004; status: completed.

02

Drugs

ibritumomab tiuxetan
03

Conditions

non-Hodgkin lymphoma (NHL)aggressive lymphoma

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