Trial intelligence / Profile preview

Anagrelide vs hydroxyurea in high-risk essential thrombocythaemia

2004-004061-15Phase 3Completed

Sponsor
Takeda
Start
Jun 2005
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in thrombocythemia comparing Anagrelide arm with Hydroxyurea arm (2 arms). Primary endpoint: Left ventricular ejection fraction (LVEF) slope over time. Started Jun 2005; status: completed.

02

Drugs

anagrelidehydroxyurea
03

Conditions

thrombocythemia

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