Trial intelligence / Profile preview

Paclitaxel/carboplatin with or without lonafarnib for first-line epithelial ovarian cancer

2004-004515-26Phase 2Completed

Sponsor
GYN Research
Start
Sep 2005
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) comparing Lonafarnib + paclitaxel + carboplatin with Paclitaxel + carboplatin (2 arms). Primary endpoint: Progression-free survival. Started Sep 2005; status: completed.

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Drugs

lonafarnibpaclitaxelcarboplatin
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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