Trial intelligence / Profile preview

Peginterferon alfa-2a ± ribavirin in HBeAg-negative chronic hepatitis B

2004-004736-30Phase 3Completed

Sponsor
Erasmus MC
Start
Dec 2004
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised trial in Chronic Hepatitis B (CHB) comparing Peginterferon alfa-2a monotherapy with Peginterferon alfa-2a plus ribavirin (2 arms). Primary endpoint: Combined virologic and biochemical response at end of follow-up. Started Dec 2004; status: completed.

02

Drugs

interferon alfaribavirin
03

Conditions

Chronic Hepatitis B (CHB)

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