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Pregabalin and aprepitant in an electrical hyperalgesia model of central sensitisation in healthy volunteers

2004-004953-24Phase 4Completed

Sponsor
University Hospital Erlangen
Start
Sep 2005
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 4, randomised, double-blind trial of pregabalin, aprepitant and parecoxib in pain, hyperalgesia and allodynia (2 arms), sponsored by University Hospital Erlangen. Primary endpoints: Changes in areas of hyperalgesia and allodynia, Pain intensity evoked by electrical stimulation and 1 more. Started Sep 2005; status: completed.

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Drugs

pregabalinaprepitantparecoxib
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Conditions

painhyperalgesiaallodynia

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