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Folic acid and allopurinol effects on endothelial function in methotrexate-treated rheumatoid arthritis
2005-000551-15Phase 4Completed
- Sponsor
- University of Dundee
- Start
- Aug 2005
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 4 trial of allopurinol, folic acid and methotrexate in rheumatoid arthritis (RA), sponsored by University of Dundee. Primary endpoints: Endothelial function by laser Doppler flowmetry with iontophoresis and Endothelial function by brachial artery flow-mediated dilatation. Started Aug 2005; status: completed.
02
Drugs
allopurinolfolic acidmethotrexate
03
Conditions
rheumatoid arthritis (RA)
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