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Phase I dose escalation study of AMN107 (nilotinib) in combination with imatinib in imatinib-resistant GIST

2005-000561-18Phase 2Completed

Sponsor
Novartis
Start
Oct 2005
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of nilotinib and imatinib in gastrointestinal stromal tumor (GIST), sponsored by Novartis. Primary endpoints: Maximum tolerated dose of AMN107 in combination with imatinib and Safety and tolerability of AMN107 + imatinib. Started Oct 2005; status: completed.

02

Drugs

nilotinibimatinib
03

Conditions

gastrointestinal stromal tumor (GIST)

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