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Influence of N-acetylcysteine on inhaled nitric oxide responses after lung ischaemia-reperfusion injury
2005-001525-28Phase 2Terminated
- Sponsor
- Imperial College London
- Start
- Feb 2006
- Modality
- DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Small Molecules
- Countries
- 1
01
Overview
Phase 2, open-label trial of nitric oxide and acetylcysteine in lung ischemia-reperfusion injury (IRI), primary graft dysfunction (PGD), heart-lung transplantation and 1 more (2 arms), sponsored by Imperial College London. Primary endpoint: Index of oxygenation (PaO2/FiO2 ratio). Started Feb 2006; status: terminated.
02
Drugs
nitric oxideacetylcysteine
03
Conditions
lung ischemia-reperfusion injury (IRI)primary graft dysfunction (PGD)heart-lung transplantationheart transplantation
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