Neoadjuvant chemotherapy and extrapleural pneumonectomy with or without hemithoracic radiotherapy in malignant pleural mesothelioma

Phase 2, randomised, open-label trial of pemetrexed and cisplatin in pleural mesothelioma (2 arms), sponsored by Swiss Group for Clinical Cancer Research. Primary endpoints: Short-term outcomes and feasibility of neoadjuvant chemotherapy and extrapleural pneumonectomy (Part 1) and Long-term outcomes and feasibility of hemithoracic radiotherapy in R0/R1 resected patients (Part 2). Started Mar 2007; status: active.