Trial intelligence / Profile preview

Insulin action in patients at increased vascular risk: modulation by antihypertensive and endocrine replacement therapy

2006-001562-16Phase 4Completed

Sponsor
Belfast Health and Social Care Trust
Start
Sep 2006
Modality
Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, double-blind trial of bendroflumethiazide, amlodipine and dehydroepiandrosterone in essential hypertension and insulin resistance (IR) (5 arms), sponsored by Belfast Health and Social Care Trust. Primary endpoint: Insulin resistance measured by hyperinsulinaemic euglycaemic glucose clamps. Started Sep 2006; status: completed.

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Drugs

bendroflumethiazideamlodipinedehydroepiandrosterone
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Conditions

essential hypertensioninsulin resistance (IR)

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