Trial intelligence / Profile preview

REFLECT-1 rosiglitazone XR monotherapy in APOE ε4-stratified mild to moderate Alzheimer's disease

2006-002038-39Phase 3Completed

Sponsor
GSK
Start
Nov 2006
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in Alzheimer's disease (AD) comparing Rosiglitazone XR monotherapy, Donepezil monotherapy and Placebo (3 arms). Primary endpoint: Change from baseline in ADAS-Cog total score at Week 24. Started Nov 2006; status: completed.

02

Drugs

rosiglitazonedonepezil
03

Conditions

Alzheimer's disease (AD)

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