Trial intelligence / Profile preview

Decitabine plus carboplatin versus carboplatin alone in progressive advanced ovarian cancer

2006-002324-41Phase 2Terminated

Sponsor
Cancer Research UK
Start
Oct 2006
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) comparing Decitabine + carboplatin with Carboplatin alone (2 arms). Primary endpoints: Primary response rate, Response rate in hMLH1-methylated subgroup and 1 more. Started Oct 2006; status: terminated.

02

Drugs

decitabinecarboplatin
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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