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Pilot study of intravitreal ranibizumab + dexamethasone, oral minocycline and verteporfin photodynamic therapy for subfoveal choroidal neovascularization due to age-related macular degeneration

2006-004292-35Phase 4Completed

Sponsor
King's College Hospital
Start
Jan 2009
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of ranibizumab, dexamethasone, minocycline and verteporfin in age-related macular degeneration (AMD) and Subretinal neovascularization, sponsored by King's College Hospital. Primary endpoints: Safety of combination intravitreal ranibizumab + dexamethasone, oral minocycline and verteporfin photodynamic therapy and Efficacy of combination intravitreal ranibizumab + dexamethasone, oral minocycline and verteporfin photodynamic therapy. Started Jan 2009; status: completed.

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Drugs

ranibizumabdexamethasoneminocyclineverteporfin
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Conditions

age-related macular degeneration (AMD)Subretinal neovascularization

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