Trial intelligence / Profile preview

PET-adapted R-MegaCHOP with early R-IFE and autologous stem cell transplant in poor-prognosis diffuse large B-cell lymphoma

2006-005254-68Phase 4Active

Sponsor
GEL/TAMO (Cooperative Spanish Group of Lymphoma/Autologous bone marrow transplant).
Start
Jan 2007
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label trial of rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone and 2 more in diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) (2 arms), sponsored by GEL/TAMO (Cooperative Spanish Group of Lymphoma/Autologous bone marrow transplant). Primary endpoint: Event-free survival at 3 years. Started Jan 2007; status: active.

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Drugs

rituximabcyclophosphamidedoxorubicinvincristineprednisone
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Conditions

diffuse large B-cell lymphoma (DLBCL)follicular lymphoma (FL)

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