Trial intelligence / Profile preview

ATRACTION trial of tretinoin added to peginterferon alfa-2a and ribavirin in prior non-responder genotype 1 chronic hepatitis C

2006-005500-14Phase 2Completed

Sponsor
University Medical Center Mainz
Start
Apr 2007
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in hepatitis C virus infection comparing Tretinoin + peginterferon alfa-2a + ribavirin with Peginterferon alfa-2a + ribavirin (2 arms). Primary endpoint: HCV viral kinetics parameter M delta. Started Apr 2007; status: completed.

02

Drugs

tretinoinpeginterferon alfa-2aribavirin
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Conditions

hepatitis C virus infection

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