Trial intelligence / Profile preview

ALFA 0703 ATRA plus chemotherapy or azacitidine salvage and azacitidine maintenance in older AML

2006-005562-39Phase 3Active

Sponsor
Assistance publique - Hôpitaux de Paris
Start
Jun 2008
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised trial in acute myeloid leukemia (AML) comparing ATRA plus chemotherapy induction, Azacitidine ± ATRA induction/salvage and Azacitidine maintenance (3 arms). Primary endpoint: Event-free survival. Started Jun 2008; status: active.

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Drugs

tretinoinazacitidine
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Conditions

acute myeloid leukemia (AML)

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