Trial intelligence / Profile preview

Phase IIa randomized double-blind dose-finding study of VS411 in treatment-naive adults with chronic HIV-1 infection

2007-002460-98Phase 2Completed

Sponsor
ViroStatics
Start
Feb 2008
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, double-blind trial of VS411, hydroxyurea and didanosine in Human immunodeficiency virus infection type 1 (3 arms), sponsored by ViroStatics. Primary endpoints: Change from baseline in plasma HIV-1 RNA, Pharmacokinetics and pharmacodynamics of didanosine and hydroxyurea and 4 more. Started Feb 2008; status: completed.

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Drugs

VS411hydroxyureadidanosine
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Conditions

Human immunodeficiency virus infection type 1

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