Trial intelligence / Profile preview

Low-dose TBI-based allogeneic hematopoietic cell transplantation vs conventional chemotherapy as consolidation for older AML in first remission

2007-003514-34Phase 3Completed

Sponsor
EBMT
Start
Sep 2008
Modality
Small Molecules, Peptides, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised trial of mitoxantrone, cytarabine, fludarabine, cyclosporine and mycophenolate mofetil in acute myeloid leukemia (AML) and myelodysplastic syndrome with excess blasts (MDS-EB) (2 arms), sponsored by EBMT. Primary endpoint: Leukemia-free survival. Started Sep 2008; status: completed.

02

Drugs

mitoxantronecytarabinefludarabinecyclosporinemycophenolate mofetil
03

Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome with excess blasts (MDS-EB)

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