Trial intelligence / Profile preview

Prolastin PET/CT study of pulmonary neutrophilic inflammation in alpha-1 antitrypsin deficiency

2007-004869-18Phase 2Completed

Sponsor
University Hospitals Birmingham
Start
Apr 2008
Modality
Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, open-label trial of alpha-1-proteinase inhibitor in alpha-1 antitrypsin deficiency (AATD) and emphysema (3 cohorts), sponsored by University Hospitals Birmingham. Primary endpoints: Global pulmonary neutrophilic inflammation, Within-patient change in PET/CT inflammation signal and 1 more. Started Apr 2008; status: completed.

02

Drugs

alpha-1-proteinase inhibitor
03

Conditions

alpha-1 antitrypsin deficiency (AATD)emphysema

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