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Randomized, Double-Blind, Placebo-Controlled Study of ISIS 301012 in Statin-Intolerant Hypercholesterolemic Subjects
2007-005140-24Phase 2Completed
- Sponsor
- Ionis Pharmaceuticals
- Start
- Oct 2007
- Modality
- Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Countries
- 1
01
Overview
Phase 2, randomised, double-blind trial in hypercholesterolemia comparing ISIS 301012 with Placebo (2 arms). Primary endpoints: Change in total cholesterol, Change in LDL cholesterol and 1 more. Started Oct 2007; status: completed.
02
Drugs
mipomersen
03
Conditions
hypercholesterolemia
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