Double-blind randomized study of sildenafil in term or late preterm neonates with severe respiratory failure and pulmonary hypertension

Phase 2, randomised, double-blind trial of sildenafil in persistent pulmonary hypertension of the newborn (PPHN) and acute respiratory decompensation (2 arms), sponsored by Ospedale Pediatrico Bambino Gesù. Primary endpoints: Reduction in oxygenation index and Oxygenation parameters over time. Started Jan 2008; status: active.