Trial intelligence / Profile preview

Reduced-intensity unrelated donor allogeneic hematopoietic progenitor transplantation with post-transplant sirolimus-based GVHD prophylaxis

2007-006416-32Phase 2Completed

Sponsor
Fundación GEL
Start
Feb 2008
Modality
RNA-Targeting Small Molecules → Nucleic Acid-Directed Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of sirolimus and tacrolimus in hematopoietic malignancies and graft-versus-host disease (GVHD) (2 arms), sponsored by Fundación GEL. Primary endpoints: Incidence and characteristics of acute and chronic graft-versus-host disease at 1 year and Comparison with historical cyclosporine A plus mycophenolate mofetil series. Started Feb 2008; status: completed.

02

Drugs

sirolimustacrolimus
03

Conditions

hematopoietic malignanciesgraft-versus-host disease (GVHD)

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