Trial intelligence / Profile preview

Phase II randomized study of Zevalin consolidation versus MabThera maintenance after initial R-CHOP response in previously untreated follicular lymphoma

2007-006601-25Phase 2Completed

Sponsor
PETHEMA
Start
Feb 2008
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial in follicular lymphoma (FL) comparing Zevalin consolidation with MabThera maintenance (2 arms). Primary endpoint: Progression-free survival. Started Feb 2008; status: completed.

02

Drugs

ibritumomab tiuxetanrituximabcyclophosphamide + doxorubicin + vincristine + prednisone + rituximab
03

Conditions

follicular lymphoma (FL)

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