Trial intelligence / Profile preview

Infliximab dose optimization in moderate to severe plaque psoriasis

2008-000454-12Phase 3Completed

Sponsor
Schering AG
Start
Nov 2008
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in plaque psoriasis comparing Infliximab every 6 weeks with Infliximab every 8 weeks plus methotrexate (2 arms). Primary endpoint: PASI-75 response rate at Week 28. Started Nov 2008; status: completed.

02

Drugs

infliximabmethotrexate
03

Conditions

plaque psoriasis

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