Trial intelligence / Profile preview

Dasatinib vs Imatinib for depletion of malignant stem cells in newly diagnosed chronic phase CML

2008-004106-13Phase 2Completed

Sponsor
NTNU
Start
Dec 2008
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial in chronic myelogenous leukemia (CML) comparing Imatinib 400 mg daily with Dasatinib 100 mg daily (2 arms). Primary endpoint: Proportion of Ph-positive cells in stem cell compartments at 6 months. Started Dec 2008; status: completed.

02

Drugs

dasatinibimatinib
03

Conditions

chronic myelogenous leukemia (CML)

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