Trial intelligence / Profile preview

Phase III study of trastuzumab emtansine versus capecitabine + lapatinib in previously trastuzumab-treated HER2-positive advanced or metastatic breast cancer

2008-005713-22Phase 3Completed

Sponsor
Roche
Start
Jan 2009
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in breast cancer comparing Trastuzumab emtansine with Capecitabine + lapatinib (2 arms). Primary endpoint: Progression-free survival. Started Jan 2009; status: completed.

02

Drugs

trastuzumab emtansinecapecitabinelapatinib
03

Conditions

breast cancer

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