Trial intelligence / Profile preview

Clofarabine Pre-Conditioning Before Allogeneic Transplantation in High-Risk AML and MDS

2008-007043-14Phase 2Unknown

Sponsor
University Hospital Southampton NHS Foundation Trust
Start
Aug 2010
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of clofarabine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), sponsored by University Hospital Southampton NHS Foundation Trust. Primary endpoints: Treatment-related mortality at day 100 post-transplant and Treatment-related mortality at 1 year post-transplant. Status: unknown.

02

Drugs

clofarabine
03

Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)

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