Trial intelligence / Profile preview

Phase IIb trial of TMC435 plus peginterferon alfa-2a and ribavirin in treatment-naive genotype 1 hepatitis C

2008-007147-13Phase 2Completed

Sponsor
Tibotec
Start
Mar 2009
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of simeprevir in hepatitis C virus infection (5 arms), sponsored by Tibotec. Primary endpoints: Sustained virologic response at Week 72 and Efficacy of four TMC435 regimens versus standard of care alone. Started Mar 2009; status: completed.

02

Drugs

simeprevir
03

Conditions

hepatitis C virus infection

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